Monique Smalls was the only Lady Raider in double digits, with 13 points on the day.
Iowa State (10-7, 1-5 Big 12) entered Sunday's game as the worst rebounding team in the Big 12, but out rebounded Tech 44-37 to give the Cyclones their first conference win of the season.
Tech (14-4, 2-4) went into the half down six, but trailed by as much as 20 points in the second half, its worst deficit all season.
The Lady Raiders will stay on the road when they take on Kansas in Lawrence this Wednesday.
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