The Immigration Institute said in a statement Monday that 17 of the migrants are from Honduras, 13 from Guatemala and three from EL Salvador. The other 40 are from Mexico.
The statement says federal and state agents rescued the migrants from a home in Reynosa, which is across the border from McAllen, Texas.
The agency says some of the Central American migrants had been held for more than three months after being kidnapped at the Reynosa bus station.
Abductions of migrants are common in northeastern Mexico, an area controlled by the Zetas and the Gulf drug cartels. In 2010, the Zetas were blamed for the mass slaying of 72 migrants in the north.